ANDRES-GIL, JOSE IGNACIO,VAN GOOL, MICHIEL LUC MARIA,BORMANS, GUY MAURITS R,VERBEEK, JOOST
申请号:
CA3003998
公开号:
CA3003998A1
申请日:
2016.12.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or 10 in vivo and to precursors of said compounds.