COMPOSÉS"MULTI-CIBLES"À ACTIVITÉ INHIBITRICE DES HISTONE-DÉSACÉTYLASES ET DE LA POLYMÉRISATION DE LA TUBULINE POUR SON UTILISATION DANS LE TRAITEMENT DU CANCER
The present invention relates to the design of new molecules called "multi - target " having a double pharmacophore and acting both as inhibitors of histone - deacetylases (hdac) and as inhibitors of tubulin polymerization. The present invention also describes the synthesis process of the molecules "multi - target " and their application in the treatment of cancer, a pharmaceutical composition comprising at least one molecule" multi - target ", as well as the use of such a composition in the treatment of cancer.
