COMPOSÉS"MULTI-CIBLES"À ACTIVITÉ INHIBITRICE DES HISTONE-DÉSACÉTYLASES ET DE LA POLYMÉRISATION DE LA TUBULINE POUR SON UTILISATION DANS LE TRAITEMENT DU CANCER

• 收藏
• 分享

专利权人:

Universite Paris-Sud

发明人:

ALAMI, Mouâd,HAMZE, Abdallah,BRION, Jean-Daniel,BIGNON, Jérôme,DUBOIS, Joëlle

申请号：

EP17701176.4

公开号：

EP3400210A2

申请日:

2017.01.05

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to the design of new molecules called "multi - target " having a double pharmacophore and acting both as inhibitors of histone - deacetylases (hdac) and as inhibitors of tubulin polymerization. The present invention also describes the synthesis process of the molecules "multi - target " and their application in the treatment of cancer, a pharmaceutical composition comprising at least one molecule" multi - target ", as well as the use of such a composition in the treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/