Exemplary apparatus and method for obtaining information regarding at least one sample can be provided. For example, at least one optical data-obtaining first arrangement can be used which is configured to obtain data for the at least one sample based on a first light radiation provided from the sample(s). At least one pressure-sensing second arrangement can also be used which is configured to measure a pressure of at least one fluid that is provided at or near the sample(s) based on a second light radiation. In addition, e.g., a housing third arrangement can at least partially enclose the first and second arrangements.