Yechiel SHAI,Avner FINK,Eliran-Moshe REUVEN,Liraz GALIA
申请号：
US15696206
公开号：
US20170362296A1
申请日:
2017.09.06
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Peptides are provided that are capable of inhibiting cell activation mediated by a Toll-like receptor (TLR) selected from TLR 1, 2, 4 or 6, said peptide comprising a sequence consisting of, or found within, the sequence of the transmembrane domain of a TLR selected from TLR 1, 2, 4 or 6 and optionally cytoplasmic and extracellular regions flanking the transmembrane domain. These peptides as well as pharmaceutical composition comprising them are useful for the treatment of TLR-mediated disease.
