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METHOD FOR ACTIVATING TREATMENT OF THE RAS
专利权人:
ИНК. (US);КОРТЕРА
发明人:
СТЬЮАРТ Деннис Р. (US)
申请号:
RU2010151472/15
公开号:
RU2010151472A
申请日:
2009.05.13
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A method of improving the cosmetic appearance of a wound on the skin, comprising administering a pharmaceutical composition containing pharmaceutically active relaxin to a subject with a wound on the skin in an amount effective to heal a wound with an improved cosmetic appearance compared to a healed wound in an untreated subject. ! 2. The method according to claim 1, in which the healed wound in color is more consistent with the surrounding skin. ! 3. The method according to claim 2, in which the healed wound further includes an interwoven assembly of collagen fibers. ! 4. The method according to claim 1, wherein said relaxin is a purified, recombinant or synthetic human relaxin H1, H2 or H3, or a relaxin agonist. ! 5. The method according to claim 1, in which relaxin is administered systemically to the subject and / or locally in a wound on the skin. ! 6. The method according to claim 1, in which the pharmaceutical composition further includes one or both of the following drugs: an antibiotic and a non-steroidal anti-inflammatory drug. ! 7. A method of reducing scarring during wound healing on the skin, comprising administering a pharmaceutical composition containing pharmaceutically active relaxin to a subject with a wound on the skin in an amount effective to heal the wound with reduced scarring, as compared to a healed wound of an untreated subject. ! 8. The method according to claim 7, in which the scar is selected from the group consisting of keloid, hypertrophic scar and atrophic skin strips. ! 9. The method according to claim 7, further comprising sanitation of the wound cavity or removal of previously existing scar tissue. ! 10. The method according to claim 7, in which relaxin is purified, recombinant or synthetic1. Способ улучшения косметического внешнего вида раны на коже, включающий введение фармацевтического состава, содержащего фармацевтически активный релаксин, субъекту с раной на коже в количестве, эффективном для заживления раны с улучшенным ко
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