Dennis J. Thiele,Rocio Gomez-Pastor,Daniel W. Neef
申请号:
US15501765
公开号:
US20170227553A1
申请日:
2015.08.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein are methods for identifying and treating subjects having conditions involving reduced HSF1 activity (e.g., diminished HSF1 activity, diminished HSF1 protein levels, increased HSF1 Ser303 phosphorylation, increased HSF1 Ser307 phosphorylation) or conditions that benefit from increasing HSF1 abundance or activity beyond physiological levels.