This invention relates to a use of an effective amount of a BET- familybromodomaininhibitor, or a pharmaceutically acceptable salt thereof, for increasing thelevel offrataxin, or for increasing the expression of frataxin. This invention alsorelates to a useof of a BET- family bromodomain inhibitor, or a pharmaceutically acceptablesaltthereof, or a composition thereof for treating a condition or a diseaseassociated withdecreased levels or activity of frataxin, including Friedreich's ataxia