KIM, Hyung Seo,CHO, Jung Hyun,KIM, Jin Cheul,KIM, Yong Il,PARK, Jae Hyun,WOO, Jong Soo
申请号：
EP17828001
公开号：
EP3485877A4
申请日:
2017.07.14
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Provided is an oral pharmaceutical formulation including sustained-release pellets containing tamsulosin hydrochloride and a pharmaceutically acceptable additive, wherein the sustained-release pellets includes about 50 wt% to about 100 wt% of particles having a particle size of about 0.50 mm to about 0.85 mm, and less than about 15wt% of particles having a particle size less than about 0.50 mm. The oral pharmaceutical formulation may have a reduced deviation in dissolution rate of tamsulosin hydrochloride and improved content uniformity among unit dosage forms, and have ensured quality due to high reproducibility of unit dosage forms.
