HONG QI,KYLE DONALD,KUPPER ROBERT,CHAPMAN ROBERT,RIDER LONN S.
申请号:
NZ60286205
公开号:
NZ602862A
申请日:
2005.03.30
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
602862 Disclosed is a process for reducing the amount of 14-hydroxycodeinone in an oxycodone hydrochloride composition to less than 25 ppm, which process comprises the step of hydrogenating the oxycodone hydrochloride composition. Preferably the process is performed with a palladium on carbon catalyst in the presence of acid. Also disclosed is the compound 8a,14-Dihydroxy-7,8-dihydrocodeinone.