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Production Method of 5-hydroxymethyl-2-furaldehyde from garlic
专利权人:
发明人:
조강진,조수묵,고정숙,김인혜
申请号:
KR1020100119377
公开号:
KR1012586950000B1
申请日:
2010.11.29
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
PURPOSE: A producing method of 5-hydroxymethyl-2-furaldehyde using garlic is provided to enable users to easily obtain the high purity 5-hydroxymethyl-2-furaldehyde with the high yield. CONSTITUTION: A producing method of 5-hydroxymethyl-2-furaldehyde using garlic comprises the following steps: high-temperature aging the garlic at 70-90 deg C for 15-40 days by sealing the garlic with a polyethylene film; hot-water extracting the aged garlic; filtering and concentrating the garlic hot-water extract; fractionating the concentrated garlic hot-water extract using ethyl acetate or butanol; separating and purifying the obtained fractions; and freeze-drying the fractions. The concentration of the garlic hot-water extract is processed by using a rotational vacuum concentrator. The fractionating process of the concentrated garlic hot-water extract is performed by using the high-performance liquid chromatography of the reverse-phase column chromatography method.본 발명은 마늘로부터 5-하이드록시메틸-2-푸랄데하이드를 생산하는 방법에 관한 것으로, 보다 구체적으로는 (S1) 마늘을 고온숙성시키는 단계; (S2) 숙성된 마늘을 열수추출하는 단계; (S3) 열수추출물을 여과 및 농축하는 단계; (S4) 에틸아세테이트 또는 부탄올로 분획하는 단계; 및 (S5) 분획물을 분리 정제하는 단계;를 포함하는 5-하이드록시메틸-2-푸랄데하이드의 생산 방법에 대한 것이다. 본 발명에 따르면 마늘을 이용하여 순도 높은 HMF를 보다 경제적이고 용이하게 고수율로 생산할 수 있다.
来源网站:
中国工程科技知识中心
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