Methods for increasing or decreasing bone density and identifying molecules

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专利权人:

发明人:

申请号：

EP10006775.0

公开号：

EP2277522B1

申请日:

2003.02.28

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The SOST gene gives rise to sclerostin, a protein that leads to apoptosis of bone progenitor cells. The invention provides methods for identifying molecules that can depress expression of the SOST gene. The invention also provides methods for identifying new sclerostin antagonists. Such molecules and antagonists are useful for increasing bone mineralization in mammals, for example, in the treatment of osteoporosis.

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中国工程科技知识中心

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http://www.ckcest.cn/home/