The problem to be solved in the present invention is to provide new Pyrrolopyrimidine compounds or its salt with NAE inhibiting effect and cell growth inhibition effect. The present invention provides formula (A) compound or its salt indicated, and NAE inhibitor, pharmaceutical composition and anti-tumor agents including the compound or its salt as active constituent.本發明要解决的問題是提供具有NAE抑制作用和細胞生長抑制效果的新的吡咯并嘧啶化合物或其鹽。本發明提供式(A)表示的化合物或其鹽,以及包括該化合物或其鹽作爲活性成分的NAE抑制劑、藥物組合物和抗腫瘤藥劑。