IMMUNE MODULATORS RELATING TO FOXO3A

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专利权人:

Arthur A. Hurwitz;Stephanie K. Watkins

发明人:

Arthur A. Hurwitz,Stephanie K. Watkins

申请号：

US13520904

公开号：

US20130022640A1

申请日:

2011.01.06

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention provides methods of enhancing an immune response to a cancer antigen in a mammal comprising inhibiting the activity of the foxo3a gene or gene product in dendritic cells in the mammal. The invention also provides methods of suppressing an immune response to an autoimmune disease antigen in a mammal comprising increasing the activity of the foxo3a gene or gene product in dendritic cells in the mammal. The invention also provides related methods of treating cancer and autoimmune diseases.

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中国工程科技知识中心

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http://www.ckcest.cn/home/