DIPEPTIDOMIMETICS AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES

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专利权人:

发明人:

LIN GANG,NATHAN CARL,SINGH PRADEEP K

申请号：

IN201747005687

公开号：

IN201747005687A

申请日:

2017.02.17

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The compounds of the present invention are represented by the following compounds having Formula I where the substituents R1 R4 L M X Y and s are as defined herein. The compounds of the present invention are also represented by the following compounds having Formula (la) Formula (lb ) or Formula (Ic) where the substituents R1 R4 RX RY X Y and s are as defined herein. These compounds are used in the treatment of cancer immunologic disorders autoimmune disorders neurodegenerative disorders or inflammatory disorders or for providing immunosuppression for transplanted organs or tissues.

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