Provided herein is a tablet cassette that can be commonly used for tablets of different types that are different in shape to some extent. The tablet cassette includes a tablet container 40, a first rotor 50, a rotating shaft 62, and a second rotor 70. The tablet container 40 has a tablet receiving space 42, 47 for randomly receiving the tablets and an outlet port 43 for discharging the tablets. At the peripheral edge portion of the first rotor 50, tablet receiving portions 51 are provided side by side for temporarily receiving the tablets. The first rotor 50 is disposed on an inner bottom portion of the tablet receiving space 42, 47. The rotating shaft 62 is operable to cause the first rotor 50 to axially rotate. The second rotor 70 has tablet receiving portions 51 at the peripheral edge portion thereof. The number of the through holes 71 formed in the second rotor 70 is smaller than the number of the tablet receiving portions 51 provided at the first rotor 50. The second rotor 70 is disposed to partition the tablet receiving space 42, 47 into a lower receiving space 42 and an upper receiving space 47. The rotating shaft 62 causes the second rotor 70 to axially rotate. The first rotor 50 and the second rotor 70 are inclined at an angle θ so as to align the outlet port 43 with an uppermost position of the rotating first rotor 50.