A tablet cassette includes a tablet container, a first rotor, a rotating shaft, and a second rotor. The tablet container has a tablet receiving space for randomly receiving the tablets and an outlet port for discharging the tablets. At the peripheral edge portion of the first rotor, tablet receiving portions are provided side by side for temporarily receiving the tablets. The first rotor is disposed on an inner bottom portion of the tablet receiving space and is rotated by the rotating shaft. The second rotor has one or more through holes. The second rotor partitions the tablet receiving space into a lower receiving space and an upper receiving space. The rotating shaft causes the second rotor to axially rotate. The first rotor and the second rotor are inclined to align the outlet port with an uppermost position of the rotating first rotor.