MODULATORS OF ATP BINDING CASSETTE TRANSPORT

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

RUAH, SARA, S., HADIDA,GROOTENHUIS, PETER, D.J.,ZHOU, JINGLAN,BEAR, BRIAN,MILLER, MARK, T.,MCCARTNEY, JASON,NUMA, MEHDI, MICHEL, JAMEL,VAN GOOR, FREDRICK,YANG, XIAOQING

申请号：

DK07755298

公开号：

DK2007756T3

申请日:

2007.04.09

申请国别(地区):

DK

年份:

2015

代理人:

摘要：

Compounds of formula Ic: or a pharmaceutically acceptable salt thereof, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to the use of the compounds of the present invention for the preparation of a medicament for treating ABC transporter mediated diseases, like cystic fibrosis.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/