The present invention refers to the bicycle system (I) special-shaped cycle,These compounds are inhibitors of one or more progeny fund enzymes, which can be used to treat diseases related to progeny fund, such as cancer, in which w is R9, etc. R1 is C1-C6 tar, etc. R2, R3 and R5 are h, halo, etc. R4 is h, halo, etc. R6 is h, halo, etc. Preferred compounds such as C1-6 hydrocarbon include: 7-amino-3 - (2,6-difluoro-3,5-methoxyphenyl) - 1,8-dimethyl-3,4-dihydropyridine-2 (1H) - ona； 7-amino-3 - (2,6-difluoro-3,5-dioxophenyl) - 8-ethyl-1La presente invencion se refiere a heterociclos biciclicos de formula (I), y composiciones farmaceuticas de estos, que son inhibidores de una o mas enzimas del FGFR y son utiles en el tratamiento de enfermedades relacionadas con el FGFR, como el cancer, donde: W es R9, etc. R1 es alquilo C1-C6, etc. R2, R3 y R5 son H, halo, etc. R4 es H, halo, etc. R6 es H, halo, etc. R7 y R8 son H, alquilo C1-C6, etc.R9 es H, alquilo C1-6,etc. los compuestos preferidos son entre otros:7-amino-3- (2,6-difluoro-3,5-dimetoxifenil)-1,8-dimetil-3,4-dihidropirido [4,3-d]pirimidin-2 (1H)-ona；7-amino-3-(2,6- difluoro-3,5-dimetoxifenil)-8-etil-1-metil-3,4-dihidropirido[4,.3-d] pirimidin-2 (1H)-ona
