A process and system for performing orthopedic surgery to create a series of channels with a subjects bone to allow a reduced pressure system to be applied directly to the bone-implant interface to enhance bone healing is provided. The process for to promote healing of a bone of a subject includes creating a three-dimensional model of the bone preoperatively planning a location of an implant relative to the model creating a plan for the location of precision channels that reach the bone-implant interface based on the model and the implant resurfacing the bone to fit the implant into or onto the bone based on the preoperative plan and milling the precision channels into the bone in the location to promote healing of the bone and/or bone implant interface and applying a pressure reduction system at the bone-implant interface to promote bone healing.