Compounds having an activity to enhance the expression of apoAI are provided. Compounds of formula (I):in which Ar1 and Ar2 are independently a phenyl, naphthyl, or monocyclic or bicyclic aromatic heterocyclic group, which may be optionally substituted —X— is —N═CZ2—, —CY2═CZ2—, —CY2Y3—CHZ2—, —S—, —O—, or the like Y1, Y2, Y3, Z1 and Z2 are independently a hydrogen, a halogen, a lower alkyl, a phenyl, or the like Z1 and Z2 may be independently a linker group that may combine with Ar2 and Ar1 to form a condensed ring m is 0 or 1, and n is 0 to 2 a prodrug thereof, a pharmaceutically acceptable salt or solvate thereof are disclosed.
