GALATSIS, PAUL,HENDERSON, JACLYN LOUISE,KORMOS, BETHANY LYN,KURUMBAIL, RAVI G.,REESE, MATTHEW RICHARD,STEPAN, ANTONIA FRIEDERIKE,VERHOEST, PATRICK ROBERT,WAGER, TRAVIS T.,PETTERSSON, MARTIN YOUNGJIN,G
申请号：
CA2941408
公开号：
CA2941408A1
申请日:
2016.09.09
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides novel imidazo[4,5-c]quinoline andimidazo[4,5-c][1,5]naphthyridine derivatives of Formula (I), and thepharmaceuticallyacceptable salts thereof(see formula I)wherein R1, R1a, R1b, R2, R4, R5, 6, X and Z are as defined in thespecification. Theinvention is also directed to pharmaceutical compositions comprising thecompoundsof Formula (I) and to use of the compounds as LRRK2 inhibitors.
