A drill guide for guiding elements, especially drill bits and implants of an implantation kit during an surgical intervention, comprises a main body (30, 70) having a gripping portion, wherein the drill guide has an upper and a lower central opening along its longitudinal axis with a through going cavity for receiving the element to be guided. A lower object contact surface is positioned on an object on or into which said element is to be guided, wherein the diameter (61) of the through going cavity can be varied by a.) radial positioning of four jaws (60) inside the cavity through a groove-slide block system (76) and/or b.) against the force of a spring at the lower free end of the guiding prolongation provided on the back side of said prolongation against the inner wall of the drill guide sleeve.