A synergistic herbicidal composition comprising Pyroxasulfone, Topramezone and Atrazine as the active components, wherein the weight ratio of Pyroxasulfone, Topramezone and Atrazine ranges from 1 to 10:1 to 10:1 to 100, is provided. Use of the synergistic herbicidal composition for controlling the growth of undesirable plants is also provided. A method of controlling the growth of undesirable plants, which comprises applying the active components Pyroxasulfone, Topramezone and Atrazine of the synergistic herbicidal composition to the undesirable plants or their growing locus or separately is also provided. A method of reducing or preventing harm caused by Pyroxasulfone when applied to plants, seeds or other reproductive parts of useful crops is also provided.
