DACQUAY, BRUNO,DOS SANTOS, CESARIO,LIND, CASEY,SANCHEZ, JR., ROBERT
申请号:
CA2698155
公开号:
CA2698155C
申请日:
2008.10.01
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Provided is a method of injecting a mixture into an eye. The mixture isprovided in adispensing chamber with an air gap located between the mixture and an interiorsurface ofa dispensing chamber housing at or near room temperature. The dispensingchamberhousing and mixture are brought to a temperature range at which the mixtureexpands andis in a more liquid state. Air is maintained in a needle after the mixtureexpands and priorto using the device for an injection. A drug release rate is selected basedupon theformation of a bolus shape of the mixture when injected. Such shape ispreviouslydetermined to have a particular surface area corresponding to a particulardrug release rate.The injection device is maintained in readiness to inject the mixture to forma shape with asurface area that results in the selected drug release rate.