Ann Marie Leen,Ulrike Gerdemann,Cliona M. Rooney,Juan F. Vera, Valdes,John R. Wilson
申请号：
US15246241
公开号：
US20160362658A1
申请日:
2016.08.24
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention encompasses methods and compositions for the generation and use of cytotoxic T lymphocytes that target multiple viruses or that are specific for multiple tumor antigens. In specific embodiments, the generation methods employ use of certain cytokines to promote proliferation and reduce cell death in an activated T cell population and/or that employ a particular bioreactor having a gas permeable membrane.
