Ann M. Leen,Ulrike Gerdemann,Cliona M. Rooney,Juan Vera,John R. Wilson
申请号：
US12862409
公开号：
US09963677B2
申请日:
2010.08.24
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention encompasses methods and compositions for the generation and use of cytotoxic T lymphocytes that target multiple viruses or that are specific for multiple tumor antigens. In specific embodiments, the generation methods employ use of certain cytokines to promote proliferation and reduce cell death in an activated T cell population and/or that employ a particular bioreactor having a gas permeable membrane.
