"HUMAN MELANOMA CELL LINE FOR TREATMENT OF MALIGNAN DISEASES, COMPOSITION FOR TREATMENT OF MELANOMA, COMPOSITION FOR TREATMENT OF HUMAN MELANOMS, PROCEDURE FOR PREPARING COMPOSITION FOR TREATMENT OF HUMAN AND MUMUMES WASTE THAT CARRY MELANOMA "
CONSEJO NACIONAL DE INVESTIGACIONE4S CIENTIFICAS Y TECNICA (CONICET);INIS BIOTECH LLC;FUNDACION SALES
发明人:
JOSE MORDOH,MARIA MARCELA,ERIKA MARIA VON EUW
申请号：
BRPI0809767
公开号：
BRPI0809767A2
申请日:
2008.04.11
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
Cell lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods. More particularly, the invention relates to diverse human melanoma cell lines for the treatment of malignant diseases, wherein the cell lines are: (a) Mel-XY1 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2830), (b) Mel-XY2 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2831), (c) Mel-XY3 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2832), (d) Mel-XX4 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2829), or (e) sub-populations thereof. The cell lines may be irradiated, thus obtaining populations with apoptotic phenotype, and populations with necrotic phenotype of such lines. The compositions may comprise adjuvants and/or immuno-modifiers, and/or autologous dendritic cells.
