Consejo Nacional de Investigaciones Cientificas Y Tecnicas (Conicet);Inis Biotech LLC;Fundacion Sales
发明人:
Mordoh, Jose,Barrio, Maria Marcela,Von Euw, Erika Maria
申请号：
AU2008238909
公开号：
AU2008238909B2
申请日:
2008.04.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
CeIl lines, compositions comprising them for the treatment of melanomas, proceduresto prepare the compositions, and treatment methods. More particularly, theinvention relates to diverse human melanoma cell lines for the treatment of malignantdiseases, wherein the cell lines are: (a) MeI-XYl (deposited at German Collectionof Microorganisms and Cell Cultures DSMZ under access number DSM ACC2830), (b)Mel-XY2 (deposited at Germán Collection of Microorganisms and Cell CulturesDSMZ under access number DSM ACC2831), (c) Mel-XY3 (deposited at GermánCollection of Microorganisms and Cell Cultures DSMZ under access number DSMACC2832), (d) Mel-XX4 (deposited at Germán Collection of Microorganismsand Cell Cultures DSMZ under access number DSM ACC2829), or (e) sub-populationsthereof. The cell lines may be irradiated, thus obtaining populations with apoptoticphenotype, and populations with necrotic phenotype of such lines. The compositionsmay comprise adjuvants and/or immuno-modif iers, and/or autologous dendriticcells.
