The invention relates to a Smoothened receptor ligand which antagonises the Hedgehog pathway, to pharmaceutical compositions and therapeutic applications thereof, processes for obtaining this compound and novel intermediates useful in these processes.本發明係有關於拮抗刺蝟因子(Hedgehog)路徑之Smoothened受體配體、其醫藥組成物及其治療性用途、此種化合物之獲得方法及可用於此等方法之新穎中間物。