I describe a method of manufacturing a dry formulation of active substances such as drug compounds. Continuous phase (eg, water) in the method, so as to form a two phase liquid system comprising droplets of the discontinuous phase, (eg, a lipid vehicle or an oil medium) a discontinuous phase comprising an active substance The dispersed nanoparticle layers one to cover the droplet at least to set the phase interface of the droplet surface nanoparticles, liquid sufficient structural integrity to allow removal of the continuous phase of the subsequent results including that brought to drop to remove the continuous phase from the nanoparticle coated droplets followed, to produce a dry formulation.薬剤化合物などの活性物質用の乾燥製剤の製造方法を記載する。本方法は、活性物質を含む不連続相(例えば、油性媒体又は脂質媒体)を、連続相(例えば、水)中に、前記不連続相の液滴を含む二相液系を形成するように分散させ、少なくとも1つのナノ粒子層が液滴を被覆するように、ナノ粒子を液滴表面の相界面に集合させ、その結果その後の連続相の除去を可能にする十分な構造完全性を液滴にもたらし、続いてナノ粒子被覆液滴から連続相を除去し、乾燥製剤を製造することを含む。
