Methods of inhibiting proliferation or immunoglobulin production of B cells using human tumor necrosis factor receptor TR-17 polypeptides

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专利权人:

Steven M. Ruben

发明人:

Steven M. Ruben,Kevin P. Baker

申请号：

US12336051

公开号：

US08518389B2

申请日:

2008.12.16

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates to a novel protein, TR17, which is a member of the tumor necrosis factor (TNF) receptor superfamily. In particular, isolated nucleic acid molecules are provided encoding the human TR17. TR17 polypeptides are also provided as anti TR17 antibodies and vectors, host cells and recombinant methods for producing the same. The invention further relates to methods of killing cells using the antibodies of the invention.

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