PSMA Development Company L.L.C.;Amgen Fremont Inc.
发明人:
申请号:
EP10184938.8
公开号:
EP2363404B8
申请日:
2002.10.23
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention includes antibodies or antigen-binding fragments thereof which bind specifically to conformational epitopes on the extracellular domain of PSMA, compositions containing one or a combination of such antibodies or antibodies or antigen-binding fragments thereof, hybridoma cell lines that produce the antibodies, and methods of using the antibodies or antigen-binding fragments thereof for cancer diagnosis and treatment. The invention also includes oligomeric forms of PSMA proteins, compositions comprising the multimers, and antibodies that selectively bind to the multimers.