An optimized sugar substitute composition is disclosed, which is a sugar substitute composition characterized with low glycemic index (GI) and sweet taste and is utilized to replace sucrose or conventional artificial sugar substitute. The sugar substitute composition comprises siraitia grosvenori extract (mogroside) and erythritol, which is capable of covering aftertaste of siraitia grosvenori extract (mogroside) and generating synergy together with siraitia grosvenori extract so as to increase sweet taste. The ratio in the composition of mogroside V and erythritol is between 50:50 and 0.1:99.9, thus to form an optimized sugar substitute composition capable of diluting siraitia grosvenori extract (mogroside), generating synergy to increase sweet taste, and providing low GI value. The produced sugar substitute composition is provided to replace sucrose or artificial sugar substitute product, to serve as high quality sweeteners required from foods, beverages, seasonings and various food additives, and to healthily promote dietary quality for the modern people.一種優化的代糖組合物,係指具有低GI升糖指數(Glycemic index,簡稱GI,又稱糖生成指數)及甜味之代糖組合物,用以取代蔗糖或習知人工代糖。該代糖組合物包含羅漢果萃取物(羅漢果甙)及具有遮蔽羅漢果萃取物(羅漢果甙)餘味(苦味)、與羅漢果萃取物(羅漢果甙)產生共合作用(synergy)增加甜味之赤藻糖醇。其中該羅漢果甙V與赤藻糖醇組成之比例介於50:50及0.1:99.9之間,以達成稀釋羅漢果萃取物(羅漢果甙),並具有產生共合作用(synergy)增加甜味及低GI升糖指數之優化代糖組合物。所製成之代糖組合物,供取代現有市面上的蔗糖或人工代糖產品,並能作為食品、飲料、調味品、及各種食品添加劑所需的優質甜味劑,且有益健康,進而助於提高現代人類的飲食品質。