Jan Torleif Pedersen,Kristian Kjaergaard,Lars Østergaard Pedersen,Ayodeji Abdur-Rasheed Asuni,Nina Helen Rosenqvist,Justus Claus Alfred Daechsel,Karsten Juhl,Lena Tagmose,Mauro Marigo,Thomas Jensen,Sø
申请号：
US16585207
公开号：
US20200109192A1
申请日:
2019.09.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PH F) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
