REGENTS OF THE UNIVERSITY OF CALIFORNIA;CATALYST BIOSCIENCES; INC.;CATALYST BIOSCIENCES, INC.
发明人:
NGUYEN, JACK,THANOS, CHRIS,RUGGLES, SANDRA, WAUGH,CRAIK, CHARLES, S.
申请号：
SG2009070467
公开号：
SG188669A1
申请日:
2003.10.02
申请国别(地区):
SG
年份:
2013
代理人:
摘要：
METHODS OF GENERATING AND SCREENING FOR PROTEASES WITH ALTERED SPECIFICITYABSTRACT Disclosed herein are methods for generating proteases with altered specificity for the target molecules they cleave is disclosed. The invention further discloses methods of using these proteases to treat diseases in which the target proteins areinvolved with. Cleaving certain target proteins at certain substrate sequences with a protease is a method for treating these pathologies.(Figure 1)
