MOLECULES D'AGONISTES DE LA SIGNALISATION WNT

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专利权人:

UNIVERSITE LIBRE DE BRUXELLES

发明人:

VANHOLLEBEKE, BENOIT

申请号：

CA3088676

公开号：

CA3088676A1

申请日:

2019.03.22

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present application relates to novel therapeutic agents, particularly to agents capable of activating (GPR)124/RECK/Frizzled/lipoprotein receptor-related protein (LRP)-mediated Wnt signaling, wherein said agents do not activate Frizzled/LRP mediated Wnt signaling in the absence of RECK and/or GPR124. The present agents are particularly useful for the prevention or treatment of neurovascular disorders or central nervous system (CNS) disorders comprising neurovascular dysfunction.

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中国工程科技知识中心

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