Provided herein are hyaluronic-acid based compositions comprising a hyaluronic acid-based polymer and a corticosteroid in the presence of a stabilizing amount of one or more stabilizing additives and related methods. The resulting compositions substantially retain their viscoelastic and related rheolotical properties under conditions of storage, processing, and use.本發明提供以玻尿酸為底質之組成物,該組成物包含在含有穩定化用量的一種或多種穩定化添加劑之下的以玻尿酸為底質之聚合物及皮質類固醇,以及相關的方法。所得的組成物實質上在貯存、處理、及使用的條件下保留其黏彈性及相關的流變特性。