Pharmaceutical compositions that include an amount of an acid addition salt of pazopanib equivalent to 10 mg/mL pazopanib and 2 to 13% w/w of a modified cyclodextrin suitable for use in an ophthalmic formulation as well as methods of making the same are described.本發明係關於醫藥組合物及製備該等之方法,該醫藥組合物包含含量相當於10 mg帕唑帕尼(pazopanib)/mL之帕唑帕尼酸加成鹽及2至13% w/w之適用於眼用調配物之經改質環糊精。