PROBLEM TO BE SOLVED: To provide an ophthalmic agent wherein coloring of a formulation is suppressed and pH is stabilized in the ophthalmic agent including ketotifen fumarate formulated with dipotassium glycyrrhizate.SOLUTION: The ophthalmic agent is obtained by including boric acid and a sugar alcohol selected from among mannitol, sorbitol or xylitol in an amount of 1.0-5.0 wt./vol.% based on the whole ophthalmic agent in a system of the ketotifen fumarate formulated with the dipotassium glycyrrhizate.COPYRIGHT: (C)2011,JPO&INPIT【課題】製剤の着色を抑制し、かつpHの安定化を図ったケトチフェンフマル酸塩とグリチルリチン酸二カリウムを配合する眼科用剤の提供。【解決手段】ケトチフェンフマル酸塩、グリチルリチン酸二カリウム配合系に、ホウ酸及びマンニトール、ソルビトール又はキシリトールから選ばれる糖アルコールを眼科用剤全体の1.0w/v%~5.0w/v%含有させた眼科用剤。【選択図】なし