USE OF (3-TRIFLUORMETHYLSULPHONYL) -N- [4-METHYL-3- (4-PYRIDIN-3-YL-PYRIMIDIN-2YL-AMINO) -PHENYL] -BENZAMIDE AGAINST BREAST CANCER, GLIOM AND ANGIOGENES
KOMPELLA, AMALA, KISHAN,ADIBHATLA KALI SATYA, BHUJANGA RAO,RACHAKONDA, SREENIVAS,VENKAIAH CHOWDARY, NANNAPANENI
申请号：
DK09717380
公开号：
DK2254882T3
申请日:
2009.03.02
申请国别(地区):
DK
年份:
2012
代理人:
摘要：
A method of preparing (3-trifluoromethylsulfonyl)-N-[4-methyl-3-nitrophenyl]-benzamide, the method comprising: providing a compound of formula VI, (3-trifluomethylsulfonyl) benzoyl chloride； condensing 4-methyl-3-nitro-aniline with the compound of formula (VI) at 30 to 40°C in chlorohydrocarbon solvent with aqueous alkali addition to obtain a compound of formula (III) (3-trifluoromethylsulfonyl)-N-[4-methyl-3-nitrophenyl]-benzamide.
