Mark Bachman,Baruch Kuppermann,Asheesh Divetia,Guann Pyng Li
申请号：
US11952626
公开号：
US08617143B2
申请日:
2007.12.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Devices, systems and methods for delivering pre-determined quantities of an active ingredient to a biological system are provided. In various embodiments, a device for controlled release of an active ingredient is provided, including a release aperture operably associated with a deflectable member, a base with a porous membrane substrate layer, and at least one chamber juxtaposed between the release aperture and the porous membrane layer. The chamber may contain a matrix including one or more active ingredients and an agent that expands when contacted with an aqueous solution. The device is suitable for implantation in a biological system and can be used for delayed and/or time release of specific drug dosages for various indications.
