Substance with specificity for human PD-1

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专利权人:

本庶 佑;小野薬品工業株式会社

发明人:

本庶 佑,柴山 史朗,竹田 和彦,松尾 政芳,吉田 隆雄,宮本 昌和

申请号：

JP2015239678

公开号：

JP6157574B2

申请日:

2015.12.08

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention relates to a substance specific to human PD-1 comprising a part that recognizes human PD-1, a part that recognizes a membrane protein in cell membrane of human PD-1-expressing cells, and linkers. Since the substance specific to human PD-1 selectively can recognize human PD-1 and a membrane protein on cell membrane of human PD-1-expressing cells and can transmit inhibitory signal of human PD-1, it is useful for therapy and/or prevention of diseases caused by immunopathy.

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