HUERTA GALINDO, VIVIAN,REYES ACOSTA, OSVALDO,GARAY PÉREZ, HILDA ELISA,CABRALES RICO, ANIA,MUSACCHIO LASA, ALEXIS,PADRÓN PALOMARES, GABRIEL RAMÓN,GONZÁLEZ LÓPEZ, LUIS JAVIER,CHINEA SANTIAGO, GLAY,FLEIT
申请号:
MYPI 20084354
公开号:
MY150685A
申请日:
2007.04.26
申请国别(地区):
MY
年份:
2014
代理人:
摘要:
THE PRESENT INVENTION IS RELATED TO A METHOD FOR BLOCKING THE INFECTION OF CELLS BY DENGUE VIRUS, BASED ON INTERFERING THE DIRECT INTERACTION OF THE VIRAL ENVELOPE PROTEIN WITH A CELLULAR RECEPTOR OR ITS INDIRECT INTERACTION WITH SAID CELLULAR RECEPTOR THROUGH A CARRIER PROTEIN, AS WELL AS RELATED USES; WHEREIN SAID CELLULAR RECEPTOR IS THE ALPHA-2 MACROGLOBULIN RECEPTOR, ALSO KNOWN AS THE LOW DENSITY RECEPTOR-RELATED PROTEIN OR AS CD91, AND SAID CARRIER PROTEIN IS HUMAN ALPHA-2 MACROGLOBULIN.