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PHARMACEUTICAL COMPOSITION COMPRISING BICYCLIC NITROGEN-CONTAINING AROMATIC HETEROCYCLIC AMIDE COMPOUND AS ACTIVE INGREDIENT
专利权人:
Astellas Pharma Inc.
发明人:
Takeyuki NAGASHIMA
申请号:
US15534318
公开号:
US20170360779A1
申请日:
2015.12.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
[Problem] Provided is a pharmaceutical composition for treating lung cancer in which mitochondrial Complex I is involved, particularly non-small cell lung cancer.[Means for Solution] The inventors of the present invention conducted examinations on a compound having an effect of inhibiting mitochondrial Complex I, and confirmed that a bicyclic nitrogen-containing aromatic heterocyclic amide compound of the present invention has the effect of inhibiting mitochondrial Complex I and that this compound exhibits an anti-tumor effect on mice bearing tumors of non-small cell lung cancer-derived cells, and therefore completed the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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