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תכשיר רוקחות המכיל תרכובת אמיד הטרוציקלית ארומטית המכילה חנקן כמרכיב פעיל
专利权人:
ASTELLAS PHARMA INC.
发明人:
申请号:
IL25266417
公开号:
IL252664D0
申请日:
2017.06.05
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
[Problem] Provided is a pharmaceutical composition for treating lung cancer involving mitochondrial Complex I, particularly non-small cell lung cancer. [Solution] After investigating compounds having a mitochondrial Complex I inhibitory effect, the present inventor completed the present invention by confirming that the bicyclic nitrogen-containing aromatic heterocyclic amide compounds of the present invention have a mitochondrial Complex I inhibitory effect, and that these compounds have an antitumor effect on mice carrying cancer derived from non-small cell lung cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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