An apheresis column loaded with a solid support comprises one or morechemokines, in particular biotinylatedchemokines, immobilized directly or indirectly on the support, in particularon a support carrying streptavidin. Also disclosed areuses of the column and the support and a method of depleting cells, inparticular leukocytes, from the peripheral blood of a personsuffering from an inflammatory condition such as Inflammatory Bowel Disease(IBD).
