A biological sensing device includes a sensor module and an electronic signal sensor. The sensor module includes a biological sensor and a sensor fixing seat. The sensor fixing base includes an electrical connection unit, and the electrical connection unit includes at least one conductive element electrically connected to the biological sensor. The conductive element is a conductive rubber with a layered structure, which is composed of alternately stacked multiple layers of electrically insulating rubber and multiple layers of conductive rubber and stacked along a first axis. The electronic signal sensor is combined with the sensor module along a second axis direction, and includes a circuit signal unit for electrically connecting with the conductive element, and a battery. The circuit signal unit has two electrical contacts, and the electrical contacts form a switch. When the electronic signal sensor is combined with the sensor module, the battery provides power to the biosensor.一種生物感測裝置包含一感測器模組，及一電子訊號傳感器。該感測器模組包括一生物感測器，及一感測器固定座。該感測器固定座包括一電連接單元，該電連接單元包括至少一電連接於該生物感測器的導電件。該導電件為一具有層狀結構的導電橡膠，由多層電絕緣橡膠和多層導電橡膠之交替堆疊組成且沿一第一軸線堆疊。該電子訊號傳感器沿一第二軸線方向結合於該感測器模組，並包括一用於與該導電件電連接的電路訊號單元，及一電池。該電路訊號單元具有二電性接點，該等電性接點形成一開關，當該電子訊號傳感器與該感測器模組結合時，該電池會提供電源至該生物感測器。
