Thomas T. Andersen,Herbert I. Jacobson,James A. Bennett,Leroy Joseph,Alberto Bryan
申请号：
US13522882
公开号：
US20130059794A1
申请日:
2011.01.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to compounds that are analogs of a cyclic peptide, cyclo[EKTOVNOGN], AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and peptidomimetics that inhibit estrogen receptor-dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.
