MEDICINAL PRODUCTS WITH IMPROVED PHARMACOKINETIC PROPERTIES

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专利权人:

BAYER PHARMA AKTIENGESELLSCHAFT

发明人:

SERNO, PETER,HEINIG, ROLAND,PAULI, KERSTIN,HAYAUCHI, YUTAKA

申请号：

AT06706994

公开号：

AT552828T

申请日:

2006.02.16

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

Formulation (I) that disintegrates quickly in the mouth, comprises vardenafil, where at least 80% of the vardenafil dose dissolves at 25[deg]C in 10 ml of physiological saline and the release rate of (I) in 900 ml of physiological saline is at least 70% within the first 5 minutes in the USP (titanium dioxide) sheet agitator device at 50 revolutions per minute at 37[deg]C. ACTIVITY : None given. MECHANISM OF ACTION : Cyclic guanosine monophosphate phosphodiesterase inhibitor. No biological data given.

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