Systems to eliminate bed bugs may generally comprise a travel article and a heating mechanism to elevate the temperature of the travel article and/or the travel article contents. The travel article may comprise a suit case, luggage, bag, backpack, garment bag, laptop bag, tote bag, purse, trunk and the like.Additionally, the system to eliminate bed bugs may further comprise a collapsible portable enclosure suitable for a traveler to transport the portable enclosure within the travel article, wherein the portable enclosure in an expanded form may comprise a volume sufficient to enclose the travel article, travel article contents, or any other item for which the user wishes to elevate the temperature of the item so as to eliminate bed bugsAmong various representative embodiments, bed bug elimination may comprise a method for manufacturing, packaging, marketing and/or selling the bed bug elimination system or device.